Clinical Trials Service

 








 
 



Contact Us:

Division of Allergy and Immunology
Creighton University
601 North 30th Street, Suite 3M-100
Omaha, NE 68131
 
 

Ph. 402.280.5975
Fx. 402.280.5961
Email

                                                                              

The Center is conducting the following new and exciting studies.

If you or someone you know is eligible and interested,

we would love to hear from you. 

Please call (402) 280-5975.

 

Patient Demographics

      The Omaha area has a population of over 750,000. The Division’s clinical research patient database alone is currently comprised of over 5,000 patients and is constantly growing through the various recruitment efforts including media advertising, health fair involvement as well as volunteer work. Our diverse patient population is drawn not only from the Omaha metropolitan area (urban/suburban), but also from the surrounding communities in Eastern Nebraska and Western Iowa (rural).

Areas of Research

Acute and chronic otitis media

Acute and chronic urticaria

Acute sinusitis

Allergic asthma

Allergic bronchopulmonary aspergillosis

Allergic conjunctivitis

Angioedema

Asthma in pregnancy

B cell immunodeficiencies

Bronchitis

Common variable immunodeficiency

Contact dermatitis

Drug allergy

Exercise induced asthma

Food allergy and food hypersensitivity

Immunizations and immunoprophylaxis

Insect allergy

Latex allergy

Management of immunotherapy

Non-allergic asthma

Nasal polyposis

 Perennial allergic rhinitis

 Seasonal allergic rhinitis

 Status asthmaticus

 T-cell immunodeficiencies

 Vasomotor rhinitis

 Urticaria

 

Procedures and Equipment Available    

 

                                       

Acoustic Rhinometry

Aeroallergen challenge

Exercise challenge

Hypertonic Saline challenge

Methacholine challenge

Bronchoprovocation Challenges

Biomarker Assays (Interleukins/Cytokines, Leukotrienes, Histamine, Tryptase, ECP)                 

Digital Electrocardiography Machine

Full Pulmonary Function Laboratory

Immediate and Delayed Hypersensitivity Skin Testing

Immunotherapy

Inpatient Beds

Nasal Allergen Challenges and Lavage

Nitric Oxide Measurements (oral/nasal)

Oral Desensitization

Parenteral Therapy Facilities

Phlebotomy

Pollen Collection

Radiology Suite for Routine X-Rays, MRIs ,CTs, Nuclear Studies

Remote Data Entry Capabilities

Spirometry

Sputum Induction

Treadmill Exercise Testing

 

Investigators

Thomas B. Casale, M.D.
Professor of Medicine and Medical Microbiology & Immunology; Chief, Division of  Allergy & Immunology  Bio

Robert G. Townley, M.D.
Professor of Medicine and Medical Microbiology & Immunology  Bio
Againdra K. Bewtra, M.B.B.S.
Associate Professor of Medicine & Biomedical Sciences Bio

Jeffrey R. Stokes, M.D.

Associate Professor of Medicine, Fellowship Program Director, Fellowship Program  Bio

Russell J. Hopp, D.O.
Professor of Pediatrics and Medicine; Chief, Division of Pediatric Allergy & Clinical Immunology Bio

 

 Staff

  Patrick De Nier:  Operations Manager

Tony Tony Romero, MS:  Budget, Contracts, & Regulatory Documents

Dian Jean Kessler, RN, BSN, CCRC:  Research Coordinator

Lori   Lori Mahon, RN, BSN,CCRC: Research Coordinator

Jani  Janie Misfieldt, MA, CCRC:  Research Coordinator

Jean Jean Casale, CMA: Research Coordinator

 

 

 Current Clinical Trials

 

Non-Invasive Ways to Evaluate Lung Disease After Treatment with Xolair

Condition: Use of medium-high dose corticosteroids, Moderate-     Severe Asthma      

Age: > 12

  

Exhaled Breath Condensate and Nitric Oxide:  Non-Invasive Evaluation of Lung Disease after Treatment with Xolair

Condition:  Allergic Asthma

Age:  > 12 years

 

▪ 26 Week Treatment Assessing the Safety of Indacaterol in Patients with Moderate to Severe Asthma

Currently Not Enrolling Subjects

Conditions:  Moderate-Severe Asthma

Age:  >12 years

 

Effect of Montelukast in Subjects with Allergic Rhinitis or Allergic Asthma

Conditions:  Allergic Asthma or Allergic Rhinitis

Age:  >12 years

 

Safety, Tolerability, Efficacy of Intravenous Doses of QAZ576 in Moderate Persistent Allergic Asthma

Condition:  Moderate Persistent Allergic Asthma

Age:  19-55 years

 

Effects of an H3 Receptor Antagonist on Congestion Following Nasal Allergen Challenge in Subject with Seasonal Allergic Rhinitis

Condition:  Seasonal Allergic Rhinitis

Age:  19-55 years

 

Safety and Efficacy of Olopaladine HCL Nasal Spray in Subjects with Seasonal Allergic Rhinitis

Condition:  Seasonal Allergic Rhinitis

Age:  6-11 years

 

Trial in Adults for the Sublingual-Oral Immunotherapy (SLIT) of Allergic Rhinoconjunctivitis With or Without Asthma Caused by Ragweed Pollen. 

Condition: Ragweed Allergies

Age: 18-50 years

 

  A Study to Test the Safety and Bronchodilatory Effect of MK-0476 in Patients with Chronic Asthma

Condition:  Mild-Moderate Asthma

Age: 15-65 years

 

A Study to Evaluate The Safety and Effect On Exercise Challenge Testing of Multiple Fixed Subcutanteous  Doses of a Humanized Ant-Interleukin-9 Monoclonal Antibody in Adults with Stable Asthma and Exercise-Induced Bronchoconstriction

Condition:  Exercise Induced Asthma

Age: 19-50

 

A Study to  Evaluate the Efficacy and Safety of Nasal Carbon Dioxide in the Treatment of Seasonal Allergic Rhinitis

Condition: Ragweed Allergies

Age: 18-65 years

   

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